Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.40 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.40 |
| ▸ | FASN | P49327 | 3/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157068 | 0.93 | DRD4 (0.46) | DRD4MEN1KMT2AHRH3KDM4E | |
| SCHEMBL20140775 | 0.86 | DRD4 (0.51) | DRD4MEN1KMT2AFAAH | |
| SCHEMBL20140777 | 0.85 | DRD4 (0.43) | DRD4MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL20141538 | 0.81 | DRD4 (0.41) | DRD4KDM4EALDH1A1HTTMTOR | |
| SCHEMBL20140044 | 0.80 | MTOR (0.54) | DRD4MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL20156931 | 0.76 | MTOR (0.51) | DRD4KDM4EALDH1A1MTORRPTOR | |
| SCHEMBL20156808 | 0.76 | MTOR (0.38) | DRD4MEN1KMT2AMTORRPTOR | |
| SCHEMBL20157066 | 0.75 | MTOR (0.46) | DRD4KDM4EALDH1A1MTORRPTOR | |
| SCHEMBL20141098 | 0.74 | MTOR (0.71) | DRD4KDM4EALDH1A1MTORRPTOR | |
| SCHEMBL20140057 | 0.74 | MTOR (0.51) | DRD4KDM4EALDH1A1MTORRPTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |