Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | HRH2 | P25021 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | HTR2C | P28335 | 3/20 | 0.44 |
| ▸ | HTR2B | P41595 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139895 | 0.86 | DRD4 (0.46) | DRD4MEN1KMT2AFAAH | |
| SCHEMBL20157068 | 0.86 | DRD4 (0.46) | DRD4HTR2BMEN1KMT2AFAAH | |
| SCHEMBL20140482 | 0.85 | DRD4 (0.51) | DRD4HRH2POLBMEN1KMT2A | |
| SCHEMBL20139955 | 0.83 | KDM4E (0.52) | DRD4HTR2AATM | |
| SCHEMBL20140777 | 0.80 | DRD4 (0.43) | DRD4MEN1KMT2A | |
| SCHEMBL20141538 | 0.75 | DRD4 (0.41) | DRD4 | |
| SCHEMBL13164025 | 0.75 | POLB (0.44) | POLB | |
| SCHEMBL20140336 | 0.74 | MAPT (0.47) | DRD4HTR2AHTR2BMEN1KMT2A | |
| SCHEMBL8844191 | 0.74 | ACHE (0.50) | DRD4MEN1KMT2AACHE | |
| SCHEMBL20141481 | 0.73 | KDM4E (0.51) | DRD4HTR2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |