Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 3/20 | 0.51 |
| ▸ | RPTOR | Q8N122 | 3/20 | 0.51 |
| ▸ | MLST8 | Q9BVC4 | 3/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 2/20 | 0.47 |
| ▸ | TACR3 | P29371 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140044 | 0.95 | MTOR (0.54) | MTORRPTORMLST8HTR7PARP1 | |
| SCHEMBL20140664 | 0.91 | MTOR (0.57) | MTORRPTORMLST8HTR7PARP1 | |
| SCHEMBL20139930 | 0.90 | MTOR (0.53) | MTORRPTORMLST8HTR7ALDH1A1 | |
| SCHEMBL20140587 | 0.87 | MTOR (0.54) | MTORRPTORMLST8PARP1ALDH1A1 | |
| SCHEMBL20139909 | 0.87 | LMNA (0.52) | MTORRPTORMLST8PARP1ALDH1A1 | |
| SCHEMBL20140693 | 0.87 | HCRTR1 (0.49) | MTORRPTORMLST8PARP1ALDH1A1 | |
| SCHEMBL20140585 | 0.87 | PPARG (0.47) | MTORRPTORMLST8PARP1TACR3 | |
| SCHEMBL20157188 | 0.87 | MTOR (0.55) | MTORRPTORMLST8ALDH1A1KDM4E | |
| SCHEMBL20157186 | 0.87 | MTOR (0.55) | MTORRPTORMLST8ALDH1A1KDM4E | |
| SCHEMBL20156824 | 0.86 | MTOR (0.56) | MTORRPTORMLST8TACR3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |