Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | KHK | P50053 | 2/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2460325 | 1.00 | GRM1 (0.45) | GRM1ALDH1A1LMNAHTR2CGRM5 | |
| SCHEMBL2460324 | 1.00 | GRM1 (0.45) | GRM1ALDH1A1LMNAHTR2CGRM5 | |
| SCHEMBL6811561 | 0.84 | AR (0.58) | AR | |
| SCHEMBL20157461 | 0.82 | GHSR (0.44) | GRM1ALDH1A1GRM5GRM2KDM4E | |
| SCHEMBL20159179 | 0.81 | ALDH1A1 (0.43) | ALDH1A1LMNAHTR2CKDM4EBRPF1 | |
| Hydrochloric Acid SCHEMBL20139302 | 0.80 | ALDH1A1 (0.45) | ALDH1A1LMNAHTR2CKDM4EBRPF1 | |
| SCHEMBL21561081 | 0.79 | ALDH1A1 (0.43) | ALDH1A1LMNAHTR2CKHKMAPT | |
| SCHEMBL21268764 | 0.79 | ADRB1 (0.61) | ALDH1A1LMNAHTR2CKHKMAPT | |
| SCHEMBL21268746 | 0.79 | ADRB1 (0.61) | ALDH1A1LMNAHTR2CKHKMAPT | |
| SCHEMBL21281577 | 0.79 | ADRB1 (0.61) | ALDH1A1LMNAHTR2CKHKMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |