Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140007 | 0.77 | SLC6A2 (0.37) | ALDH1A1HTR6 | |
| SCHEMBL20139813 | 0.76 | NAMPT (0.42) | — | |
| SCHEMBL20141381 | 0.76 | DAO (0.43) | FFAR4FFAR1 | |
| SCHEMBL27607731 | 0.74 | HTR6 (0.50) | ALDH1A1HTR6OPRL1 | |
| SCHEMBL20140728 | 0.74 | MTOR (0.46) | ALDH1A1AR | |
| SCHEMBL5028368 | 0.73 | HRH3 (0.45) | TMEM97FFAR1 | |
| SCHEMBL22068710 | 0.72 | KCNH2 (0.44) | TMEM97FFAR4ARFFAR1 | |
| SCHEMBL24984505 | 0.71 | ALDH1A1 (0.43) | ALDH1A1HTR6OPRL1 | |
| SCHEMBL30163981 | 0.71 | ALDH1A1 (0.43) | ALDH1A1HTR6OPRL1 | |
| SCHEMBL320435 | 0.71 | FFAR1 (0.44) | FFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |