Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17701291 | 0.86 | NSD2 (0.48) | HTTMEN1KMT2AL3MBTL1NSD2 | |
| SCHEMBL320435 | 0.83 | FFAR1 (0.44) | HRH3HTTMEN1KMT2AL3MBTL1 | |
| SCHEMBL1935310 | 0.81 | MEN1 (0.47) | HRH3HTTMEN1KMT2AL3MBTL1 | |
| SCHEMBL2881402 | 0.81 | PPARA (0.49) | HRH3HTTMEN1KMT2AL3MBTL1 | |
| SCHEMBL4147783 | 0.81 | ESRRG (0.49) | HTTMEN1KMT2AL3MBTL1 | |
| SCHEMBL1027884 | 0.81 | MEN1 (0.47) | HTTMEN1KMT2AL3MBTL1CTBP2 | |
| SCHEMBL21247482 | 0.80 | KMT2A (0.63) | HTTMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL11898599 | 0.80 | MEN1 (0.46) | HRH3HTTMEN1KMT2AL3MBTL1 | |
| SCHEMBL21997106 | 0.80 | KMT2A (0.46) | HTTMEN1KMT2AL3MBTL1CYP2A6 | |
| SCHEMBL1845384 | 0.80 | MEN1 (0.46) | HTTMEN1KMT2AL3MBTL1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180370927-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-12-27 | — | — | US | disclosed |
| US-20080221082-A1 | Ligands of Integrin Receptors | ABBOTT GMBH & CO. KG (DE) | 2008-09-11 | — | — | US | disclosed |
| EP-1286673-B1 | LIGANDS OF INTEGRIN RECEPTORS | BASF AG (DE) | 2005-05-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180370927-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | PRF1, MPO, NOX3 | HRH3 2945/4885HTT 4832/4885MEN1 3642/4885 |
| US-20080221082-A1 | Ligands of Integrin Receptors | ITGB3, ITGAV, ITGA2B | HRH3 1034/4885HTT 4750/4885MEN1 4463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.