Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140463 | 0.78 | APP (0.59) | APPMAPTSNCA | |
| SCHEMBL19556864 | 0.78 | APP (0.66) | APPMAPTSNCA | |
| SCHEMBL15596831 | 0.71 | MAPT (0.54) | APPMAPTSNCACYP2A6 | |
| SCHEMBL30668499 | 0.70 | MAPT (0.68) | APPMAPTSNCAL3MBTL1 | |
| SCHEMBL2762740 | 0.70 | MAPT (0.68) | APPMAPTSNCAL3MBTL1 | |
| SCHEMBL8143544 | 0.69 | LMNA (0.39) | MAPTL3MBTL1 | |
| SCHEMBL21298993 | 0.69 | APP (0.74) | APPMAPTSNCA | |
| SCHEMBL4907472 | 0.67 | APP (0.59) | APPMAPTSNCAHTTNPSR1 | |
| SCHEMBL531432 | 0.66 | LMNA (0.47) | MAPTL3MBTL1 | |
| SCHEMBL22769623 | 0.65 | ALDH1A1 (0.33) | MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538161-A1 | METHODS FOR MULTI-DOSE SYNTHESIS OF [F-18]FDDNP FOR CLINICAL SETTINGS | The Regents of The University of California (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089491-A1 | METHODS FOR MULTI-DOSE SYNTHESIS OF [F-18]FDDNP FOR CLINICAL SETTINGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-05-17 | — | — | WO | disclosed |