⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140271 | 0.78 | THRB (0.32) | — | |
| SCHEMBL20140274 | 0.75 | PDE4A (0.33) | — | |
| SCHEMBL20140203 | 0.74 | GRM2 (0.31) | — | |
| SCHEMBL20161104 | 0.73 | PRMT5 (0.30) | — | |
| SCHEMBL20140297 | 0.73 | TGFBR1 (0.32) | — | |
| SCHEMBL20142239 | 0.68 | PTPN1 (0.41) | — | |
| SCHEMBL20139763 | 0.64 | KCNK13 (0.34) | — | |
| SCHEMBL22574860 | 0.58 | L3MBTL1 (0.33) | — | |
| SCHEMBL23715848 | 0.54 | RAB9A (0.38) | — | |
| SCHEMBL6346128 | 0.54 | KDM4E (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12435080-B2 | sGC stimulators | TISENTO THERAPEUTICS INC. (US) | 2025-10-07 | — | — | US | disclosed |
| US-20220017515-A1 | sGC STIMULATORS | TISENTO THERAPEUTICS INC. | 2022-01-20 | — | — | US | disclosed |
| US-11180493-B2 | SGC stimulators | CYCLERION THERAPEUTICS, INC. (US) | 2021-11-23 | — | — | US | disclosed |
| US-20200071318-A1 | SGC STIMULATORS | TISENTO THERAPEUTICS INC. | 2020-03-05 | — | — | US | disclosed |
| EP-3538520-A2 | SGC STIMULATORS | Cyclerion Therapeutics, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089330-A2 | SGC STIMULATORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |