Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25317158 | 0.80 | MEN1 (0.46) | ALDH1A1LMNAMAPTKDM4EMAPK1 | |
| SCHEMBL29475509 | 0.80 | MEN1 (0.46) | ALDH1A1LMNAMAPTKDM4EMAPK1 | |
| SCHEMBL20140581 | 0.78 | KDM4E (0.52) | ALDH1A1LMNAMAPTKDM4EHSD17B10 | |
| SCHEMBL20140473 | 0.75 | KDM4E (0.51) | ALDH1A1LMNAKDM4EMAPK1MEN1 | |
| SCHEMBL20140026 | 0.74 | KDM4E (0.57) | ALDH1A1LMNAKDM4EMAPK1HSD17B10 | |
| SCHEMBL4315345 | 0.72 | ALDH1A1 (0.64) | ALDH1A1KDM4EMAPK1HSD17B10CDK5 | |
| SCHEMBL4315340 | 0.72 | ALDH1A1 (0.64) | ALDH1A1KDM4EMAPK1HSD17B10CDK5 | |
| SCHEMBL20141517 | 0.72 | KDM4E (0.49) | ALDH1A1LMNAMAPTKDM4EHSD17B10 | |
| SCHEMBL27084449 | 0.71 | ERN1 (0.48) | ALDH1A1LMNAMAPTKDM4EMAPK1 | |
| SCHEMBL30792771 | 0.71 | ERN1 (0.48) | ALDH1A1LMNAMAPTKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |