Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ME2 | P23368 | 1/20 | 0.40 |
| ▸ | ME1 | P48163 | 1/20 | 0.40 |
| ▸ | ME3 | Q16798 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140581 | 0.85 | KDM4E (0.52) | KDM4ESMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL20140026 | 0.78 | KDM4E (0.57) | KDM4ESMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL20140544 | 0.78 | ALDH1A1 (0.48) | KDM4EALDH1A1ATM | |
| SCHEMBL25317158 | 0.77 | MEN1 (0.46) | KDM4ESMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL29475509 | 0.77 | MEN1 (0.46) | KDM4ESMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL26118888 | 0.76 | PARP1 (0.53) | KDM4EALDH1A1 | |
| SCHEMBL30546064 | 0.76 | PARP1 (0.53) | KDM4EALDH1A1 | |
| SCHEMBL20140014 | 0.74 | GRM1 (0.54) | — | |
| SCHEMBL20804512 | 0.73 | ALDH1A1 (0.56) | KDM4ESMN1; SMN2ALDH1A1HSD17B10HRH3 | |
| SCHEMBL20140035 | 0.73 | GRM1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |