Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 1/20 | 0.48 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.48 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.48 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.48 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.46 |
| ▸ | GNRHR | P30968 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | YAP1 | P46937 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16992177 | 0.86 | STS (0.47) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL20142115 | 0.83 | EED (0.48) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL3907013 | 0.83 | KDM4E (0.55) | KDM4EPKMALDH1A1TP53MAPT | |
| SCHEMBL25487258 | 0.82 | ALDH1A1 (0.53) | KDM4EALDH1A1CYP2C9CYP2C19TP53 | |
| SCHEMBL17982809 | 0.81 | KDM4E (0.56) | KDM4EPKMTGFBR1YAP1TP53 | |
| SCHEMBL29181014 | 0.81 | NAMPT (0.52) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL12128826 | 0.80 | SLC6A4 (0.49) | KDM4EPKMGNRHRYAP1TLR7 | |
| SCHEMBL16113579 | 0.80 | GPR119 (0.61) | KDM4EPKMCYP2C19TP53LMNA | |
| SCHEMBL30344060 | 0.79 | GPR119 (0.54) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL25155201 | 0.79 | GPR119 (0.54) | EEDRBBP4SUZ12EZH2AEBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |