Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 1/20 | 0.48 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.48 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.48 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.48 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GNRHR | P30968 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140685 | 0.83 | EED (0.48) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL15058311 | 0.82 | KDM4E (0.56) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL20971864 | 0.79 | EPHX2 (0.56) | KDM4EPKMTGFBR1KMT2AGPR119 | |
| SCHEMBL20971744 | 0.78 | KDM4E (0.48) | KDM4EPKMTGFBR1KMT2AGNRHR | |
| SCHEMBL20971782 | 0.77 | STS (0.48) | KDM4EPKMKMT2AGPR119ALDH1A1 | |
| SCHEMBL3907013 | 0.77 | KDM4E (0.55) | KDM4EPKMKMT2AGPR119ALDH1A1 | |
| SCHEMBL31071538 | 0.76 | TGFBR1 (0.51) | KDM4EPKMTGFBR1KMT2AGNRHR | |
| SCHEMBL16992177 | 0.76 | STS (0.47) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL1295322 | 0.76 | GPR119 (0.61) | GPR119 | |
| SCHEMBL24717826 | 0.76 | EED (0.48) | EEDRBBP4SUZ12EZH2AEBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |