Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 7/20 | 0.44 |
| ▸ | DRD2 | P14416 | 5/20 | 0.36 |
| ▸ | HTR2A | P28223 | 5/20 | 0.36 |
| ▸ | HTR7 | P34969 | 4/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 7/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139961 | 0.83 | DRD4 (0.45) | DRD4DRD2HTR2AHTR7DRD3 | |
| SCHEMBL20156841 | 0.82 | DRD4 (0.51) | DRD4DRD2HTR2AHTR7DRD3 | |
| SCHEMBL20141633 | 0.81 | DRD4 (0.46) | DRD4DRD3ALDH1A1 | |
| SCHEMBL20141994 | 0.76 | DRD4 (0.44) | DRD4DRD2HTR2AHTR7DRD3 | |
| SCHEMBL20141996 | 0.76 | DRD4 (0.46) | DRD4DRD2HTR2ADRD3KDM4E | |
| SCHEMBL20139927 | 0.74 | DRD4 (0.53) | DRD4DRD2HTR2AHTR7DRD3 | |
| SCHEMBL20139931 | 0.70 | LMNA (0.43) | DRD4DRD2DRD3ALDH1A1 | |
| SCHEMBL20141636 | 0.69 | DRD4 (0.41) | DRD4DRD2HTR2AHTR7DRD3 | |
| SCHEMBL20157436 | 0.69 | ALDH1A1 (0.42) | DRD4ALDH1A1 | |
| SCHEMBL20157438 | 0.69 | ALDH1A1 (0.41) | DRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |