Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 3/20 | 0.56 |
| ▸ | RPTOR | Q8N122 | 3/20 | 0.56 |
| ▸ | MLST8 | Q9BVC4 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 9/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 9/20 | 0.38 |
| ▸ | PARP3 | Q9Y6F1 | 9/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | PARP6 | Q2NL67 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140981 | 0.91 | MTOR (0.46) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20140935 | 0.91 | MTOR (0.53) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20141210 | 0.89 | MTOR (0.65) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20141035 | 0.84 | MTOR (0.45) | MTORRPTORMLST8KDM4E | |
| SCHEMBL20141671 | 0.80 | MTOR (0.44) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20142302 | 0.79 | MTOR (0.55) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20140929 | 0.78 | MTOR (0.57) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20133682 | 0.77 | MTOR (0.82) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20140814 | 0.77 | MTOR (0.45) | MTORRPTORMLST8ALDH1A1CA12 | |
| SCHEMBL20140851 | 0.76 | MTOR (0.44) | MTORRPTORMLST8KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| US-20160022830-A1 | METHODS FOR PREPARING POLYMERIC REAGENTS | NEKTAR THERAPEUTICS | 2016-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160022830-A1 | METHODS FOR PREPARING POLYMERIC REAGENTS | PAM, ALKBH3, DNPEP | MTOR 3982/4885RPTOR 4542/4885MLST8 3123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.