SCHEMBL20141

SCHEMBL20141

Cn1cc(C(=O)O)c(C(F)F)n1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
IRAK4 Q9NWZ3 6/20 0.35
ACACB O00763 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
GAA P10253 3/20 0.33
KLKB1 P03952 1/20 0.33
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
LMNA P02545 2/20 0.33
POLB P06746 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28726067 0.98 IRAK4 (0.35) IRAK4ACACBMEN1KMT2AGAA
Hydrochloric Acid SCHEMBL8932295 0.98 IRAK4 (0.34) IRAK4ACACBMEN1KMT2AGAA
Hydrochloric Acid SCHEMBL1032497 0.98 IRAK4 (0.34) IRAK4ACACBMEN1KMT2AGAA
SCHEMBL8932291 0.92 CYP11B1 (0.33) IRAK4ACACBMEN1KMT2AKLKB1
SCHEMBL31265253 0.88 MEN1 (0.32) ACACBMEN1KMT2AKLKB1
SCHEMBL460661 0.86 LMNA (0.34) GAALMNAPOLBCYP1A2CYP2C9
SCHEMBL14010542 0.85 LMNA (0.35) IRAK4ACACBKMT2AGAAKLKB1
SCHEMBL345169 0.84 ADORA2A (0.37) IRAK4ACACBGAAKLKB1CYP11B1
SCHEMBL15774097 0.84 KLKB1 (0.35) IRAK4ACACBGAAKLKB1CYP11B1
SCHEMBL439674 0.84 KLKB1 (0.35) IRAK4ACACBGAAKLKB1CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2945 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4127157-B1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS ENCODIA INC (US) 2026-02-11 EP claimed
CN-120118034-A Synthesis method of 3-difluoromethyl-1-methylpyrazole-4-carboxylic acid 辽宁龙田化工科技有限公司 2025-06-10 CN claimed
CN-119930518-A 3- (Difluoromethyl) -1-methyl-1H-pyrazole derivatives, and preparation method and application thereof 南开大学 2025-05-06 CN claimed
CN-119613339-B Fluoconazole fungus method for synthesizing amide 齐鲁晟华制药有限公司 2025-05-06 CN claimed
WO-2025074339-A1 A PROCESS FOR PREPARATION OF CARBOXAMIDE COMPOUNDS AND INTERMEDIATES THEREOF UPL LIMITED (IN) 2025-04-10 WO claimed
CN-119707816-A Pyrazole hydrazide derivative containing diphenyl ether unit as well as preparation method and application thereof 江苏海洋大学 2025-03-28 CN claimed
CN-119613339-A Fluoconazole fungus method for synthesizing amide 齐鲁晟华制药有限公司 2025-03-14 CN claimed
CN-119431246-A Bispyrimidine marked with dichloro benzene ring carbon-14 and preparation method thereof 浙江爱索拓科技有限公司 2025-02-14 CN claimed
EP-4422404-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2024-09-04 EP claimed
CN-118562431-A Rock shield glue and tile quick paving demolition-free construction method 山东卓高新材料有限公司 2024-08-30 CN claimed
EP-1906730-A2 SEED TREATMENT METHOD AND PESTICIDAL COMPOSITION Syngeta Participations AG (CH) 2008-04-09 EP claimed
US-20080051446-A1 Heterocyclocarboxamide Derivatives SYNGENTA CROP PROTECTION, INC. 2008-02-28 US claimed
WO-2007110173-A2 FUNGICIDAL ACTIVE SUBSTANCE COMBINATIONS BAYER CROPSCIENCE AG (DE) 2007-10-04 WO claimed
WO-2007104658-A2 METHOD OF INDUCING TOLERANCE OF PLANTS AGAINST BACTERIOSES BASF SE (DE) 2007-09-20 WO claimed
EP-1813152-A1 Fungicidal mixture based on 3,4-disubstituted biphenylanilides BASF AKTIENGESELLSCHAFT (DE) 2007-08-01 EP claimed
US-7241721-B2 carboxamide derivatives as active ingredients which have microbiocidal activity, in particular fungicidal activity SYNGENTA CROP PROTECTION, INC. (US) 2007-07-10 US claimed
EP-1480955-B1 O-CYCLOPROPYL-CARBOXANILIDES AND THEIR USE AS FUNGICIDES SYNGENTA PARTICIPATIONS AG (CH) 2007-06-27 EP claimed
WO-2007031323-A1 PROCESS FOR THE PRODUCTION OF AMIDES SYNGENTA PARTICIPATIONS AG. (CH) 2007-03-22 WO claimed
WO-2007003319-A2 SEED TREATMENT METHOD AND PESTICIDAL COMPOSITION SYNGENTA PARTICIPATIONS AG (CH) 2007-01-11 WO claimed
CN-1245384-C Carboxamides as fungicides in agriculture SYNGENTA PARTICIPATIONS AG (CH) 2006-03-15 CN claimed