Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | DCAF1 | Q9Y4B6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141 | 0.86 | IRAK4 (0.35) | LMNAPOLBGAARAB9ACYP1A2 | |
| SCHEMBL3258066 | 0.86 | GAA (0.33) | LMNAPOLBGAARAB9ACYP1A2 | |
| SCHEMBL1085956 | 0.85 | ADORA2A (0.36) | LMNAPOLBGAARAB9AL3MBTL1 | |
| SCHEMBL28726067 | 0.84 | IRAK4 (0.35) | GAA | |
| Hydrochloric Acid SCHEMBL1032497 | 0.84 | IRAK4 (0.34) | LMNAPOLBGAA | |
| Hydrochloric Acid SCHEMBL8932295 | 0.84 | IRAK4 (0.34) | LMNAPOLBGAA | |
| SCHEMBL8932291 | 0.82 | CYP11B1 (0.33) | LMNAPOLB | |
| SCHEMBL11893202 | 0.80 | PPARA (0.36) | LMNAPOLBGAARAB9ACYP1A2 | |
| SCHEMBL1866000 | 0.80 | GAA (0.36) | LMNAPOLBGAA | |
| SCHEMBL963986 | 0.80 | BAZ2B (0.43) | LMNAGAARAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595962-B1 | PROCESS FOR THE PREPARATION OF ESTERS OF 1-SUBSTITUTED-3-FLUOROALKYL-PYRAZOLE-4-CARBOXYLIC ACIDS | SOLVAY (BE) | 2018-07-11 | — | — | EP | disclosed |
| US-8981116-B2 | Process for the preparation of esters of 1-substituted-3-fluoroalkyl-pyrazole-4-carboxylic acids | SOLVAY SA (BE) | 2015-03-17 | — | — | US | disclosed |
| EP-2595962-A1 | PROCESS FOR THE PREPARATION OF ESTERS OF 1-SUBSTITUTED-3-FLUOROALKYL-PYRAZOLE-4-CARBOXYLIC ACIDS | SOLVAY SA (BE) | 2013-05-29 | — | — | EP | disclosed |
| US-20130123510-A1 | Process for the preparation of esters of 1-substituted-3-fluoroalkyl-pyrazole-4-carboxylic acids | SOLVAY SA (BE) | 2013-05-16 | — | — | US | disclosed |
| WO-2012010692-A1 | PROCESS FOR THE PREPARATION OF ESTERS OF 1-SUBSTITUTED-3-FLUOROALKYL-PYRAZOLE-4-CARBOXYLIC ACIDS | SOLVAY SA (BE) | 2012-01-26 | — | — | WO | disclosed |
| US-7939673-B2 | Process for preparing 3-dihalomethyl-pyrazole-4-carboxylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2011-05-10 | — | — | US | disclosed |
| US-20090326242-A1 | PROCESS FOR PREPARING 3-DIHALOMETHYL-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090326242-A1 | PROCESS FOR PREPARING 3-DIHALOMETHYL-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | HRH4, SUV39H2, SUV39H1 | LMNA 4007/4885POLB 1946/4885GAA 962/4885 |
| US-20130123510-A1 | Process for the preparation of esters of 1-substituted-3-fluoroalkyl-pyrazole-4-carboxylic acids | CYP2F1, KHK, CYP4F3 | LMNA 1953/4885POLB 2256/4885GAA 1327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.