Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 9/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439674 | 0.94 | KLKB1 (0.35) | CYP11B1CYP11B2KLKB1IRAK4LMNA | |
| Hydrochloric Acid SCHEMBL38654637 | 0.92 | KLKB1 (0.34) | CYP11B1CYP11B2KLKB1IRAK4LMNA | |
| SCHEMBL20141 | 0.92 | IRAK4 (0.35) | CYP11B1CYP11B2KLKB1IRAK4LMNA | |
| Hydrochloric Acid SCHEMBL8932295 | 0.90 | IRAK4 (0.34) | CYP11B1CYP11B2KLKB1IRAK4LMNA | |
| SCHEMBL28726067 | 0.90 | IRAK4 (0.35) | CYP11B1CYP11B2KLKB1IRAK4ACACB | |
| Hydrochloric Acid SCHEMBL1032497 | 0.90 | IRAK4 (0.34) | CYP11B1CYP11B2KLKB1IRAK4LMNA | |
| SCHEMBL9266924 | 0.83 | LMNA (0.35) | IRAK4LMNAPOLBACACB | |
| SCHEMBL460661 | 0.82 | LMNA (0.34) | LMNAPOLB | |
| SCHEMBL3258066 | 0.82 | GAA (0.33) | LMNAPOLBMEN1KMT2A | |
| SCHEMBL31265253 | 0.81 | MEN1 (0.32) | KLKB1ACACBMEN1KMT2ANR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728198-A1 | PROCESS FOR THE MANUFACTURE OF PYRAZOLE CARBOXYLIC DERIVATIVES AND PRECURSORS THEREOF | SOLVAY SA (BE) | 2020-10-28 | — | — | EP | disclosed |
| US-5498624-A | PLANT FUNGICIDES | MONSANTO COMPANY (US) | 1996-03-12 | — | — | US | disclosed |