SCHEMBL20141088

SCHEMBL20141088

CCCCC/C=C\CCOC(=O)CCCCCCCN(CCCCCCCC(=O)OCC/C=C\CCCCC)CCOC(=O)CCCN(C)C

nearest known ligand 0.62

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.62
MGLL Q99685 1/20 0.49
ALDH1A1 P00352 1/20 0.48
MAPT P10636 1/20 0.48
THRB P10828 1/20 0.48
CNR1 P21554 1/20 0.48
DGKA P23743 2/20 0.48
EPHX2 P34913 4/20 0.46
PRKCE Q02156 1/20 0.45
PRKCQ Q04759 1/20 0.45
PRKCD Q05655 1/20 0.45
PRKCA P17252 1/20 0.45
FAAH O00519 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15027019 0.96 DNM1 (0.62) DNM1MGLLALDH1A1MAPTTHRB
SCHEMBL21380037 0.93 MGLL (0.59) DNM1MGLLALDH1A1MAPTTHRB
SCHEMBL20139488 0.92 DNM1 (0.54) DNM1MGLLALDH1A1MAPTTHRB
SCHEMBL20149761 0.90 DNM1 (0.54) DNM1MGLLALDH1A1MAPTTHRB
SCHEMBL25076670 0.89 DNM1 (0.59) DNM1MGLLALDH1A1MAPTTHRB
SCHEMBL24728808 0.89 MGLL (0.54) DNM1MGLLALDH1A1MAPTTHRB
SCHEMBL9717053 0.88 DNM1 (0.64) DNM1MGLLALDH1A1MAPTTHRB
SCHEMBL9717060 0.88 DNM1 (0.64) DNM1MGLLALDH1A1MAPTTHRB
SCHEMBL24627685 0.88 MGLL (0.59) DNM1MGLLALDH1A1MAPTTHRB
SCHEMBL20149557 0.87 DNM1 (0.72) DNM1MAPTTHRBDGKAFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11851389-B2 Cationic lipids for nucleic acid delivery and preparation thereof RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2023-12-26 US claimed
EP-3538515-B1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF UNIV RAMOT (IL) 2022-07-20 EP claimed
US-20190292130-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2019-09-26 US claimed
EP-3538515-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF Ramot at Tel-Aviv University Ltd. (IL) 2019-09-18 EP claimed
WO-2018087753-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF TECHNOLOGY INNOVATION MOMENTUM FUND (ISRAEL) LIMITED PARTNERSHIP (IL) 2018-05-17 WO claimed
US-20190292130-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2019-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11851389-B2 Cationic lipids for nucleic acid delivery and preparation thereof NPC1L1, NPC1, CETP DNM1 165/4885MGLL 138/4885ALDH1A1 3981/4885
US-20190292130-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF NPC1L1, NPC1, CETP DNM1 165/4885MGLL 138/4885ALDH1A1 3981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.