SCHEMBL24728808

SCHEMBL24728808

CCCCC/C=C\C/C=C\CCCCCCCCN(CCCCCCCCCC=O)CCOC(=O)CCCN(C)C

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.54
DNM1 Q05193 1/20 0.53
ALDH1A1 P00352 2/20 0.53
MAPT P10636 1/20 0.53
THRB P10828 1/20 0.53
CNR1 P21554 1/20 0.53
FAAH O00519 2/20 0.47
TRPV1 Q8NER1 1/20 0.46
CYP3A4 P08684 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
DGKA P23743 1/20 0.44
HTR2A P28223 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21380037 0.95 MGLL (0.59) MGLLDNM1ALDH1A1MAPTTHRB
SCHEMBL22907463 0.90 MGLL (0.53) MGLLDNM1ALDH1A1MAPTTHRB
SCHEMBL25076629 0.89 MGLL (0.56) MGLLDNM1ALDH1A1MAPTTHRB
SCHEMBL20141088 0.89 DNM1 (0.62) MGLLDNM1ALDH1A1MAPTTHRB
SCHEMBL24627685 0.89 MGLL (0.59) MGLLDNM1ALDH1A1MAPTTHRB
SCHEMBL24627584 0.86 MGLL (0.55) MGLLDNM1ALDH1A1MAPTTHRB
SCHEMBL24627544 0.86 MGLL (0.55) MGLLDNM1ALDH1A1MAPTTHRB
SCHEMBL24627656 0.86 MGLL (0.55) MGLLDNM1ALDH1A1MAPTTHRB
SCHEMBL24627811 0.86 MGLL (0.59) MGLLDNM1ALDH1A1MAPTTHRB
SCHEMBL19695716 0.86 MGLL (0.64) MGLLDNM1ALDH1A1MAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022168085-A1 LIPIDS SUITABLE FOR NUCLEIC ACID DELIVERY RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2022-08-11 WO disclosed