Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21360342 | 0.86 | GPR119 (0.48) | ALDH1A1 | |
| SCHEMBL20141301 | 0.80 | MAPK1 (0.42) | FFAR1ALDH1A1MAPTHTTLMNA | |
| SCHEMBL29873861 | 0.78 | FFAR1 (0.55) | CACNA1GFFAR1PPARG | |
| SCHEMBL899763 | 0.78 | NCF1 (0.50) | ALDH1A1MAPTHTTMAPK1MEN1 | |
| SCHEMBL20141303 | 0.78 | MAPK1 (0.43) | FFAR1ALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL25154295 | 0.77 | FFAR1 (0.47) | FFAR1PPARG | |
| SCHEMBL4131376 | 0.76 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNAMAPK1GAA | |
| SCHEMBL23390023 | 0.76 | BRD4 (0.36) | LMNAL3MBTL1TSHRCYP3A4CYP2C19 | |
| SCHEMBL31539414 | 0.75 | USP30 (0.45) | MAPTLMNAKMT2A | |
| SCHEMBL31539300 | 0.75 | USP30 (0.45) | MAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |