Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 5/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140336 | 0.89 | MAPT (0.47) | KDM4EALDH1A1CHRM4DRD4DRD3 | |
| SCHEMBL20139884 | 0.86 | BDKRB1 (0.47) | BDKRB1KDM4EALDH1A1NPSR1CHRM4 | |
| SCHEMBL20140966 | 0.81 | MTOR (0.47) | BDKRB1KDM4EALDH1A1DRD4DRD3 | |
| SCHEMBL20156971 | 0.79 | CHRM4 (0.41) | KDM4EALDH1A1CHRM4DRD4DRD3 | |
| SCHEMBL20140897 | 0.78 | MTOR (0.45) | KDM4EALDH1A1MAPK1CYP2C9CYP2C19 | |
| SCHEMBL20140733 | 0.78 | KDM4E (0.48) | BDKRB1KDM4EALDH1A1NPSR1DRD4 | |
| SCHEMBL20129666 | 0.77 | MTOR (0.62) | BDKRB1KDM4EALDH1A1DRD4DRD3 | |
| SCHEMBL20133548 | 0.77 | MTOR (0.56) | BDKRB1KDM4EALDH1A1DRD4DRD3 | |
| SCHEMBL20139958 | 0.76 | NAMPT (0.53) | KDM4EALDH1A1DRD4DRD3DRD2 | |
| SCHEMBL20141681 | 0.75 | MTOR (0.44) | BDKRB1KDM4EALDH1A1NPSR1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |