Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140336 | 0.82 | MAPT (0.47) | CHRM4DRD4HTTMAPTGFER | |
| SCHEMBL20141292 | 0.79 | BDKRB1 (0.47) | CHRM4DRD4DRD2DRD3KDM4E | |
| SCHEMBL15831837 | 0.72 | FFAR4 (0.54) | HTTMAPTGFERSMN1; SMN2FFAR4 | |
| SCHEMBL20140897 | 0.72 | MTOR (0.45) | HTTSMN1; SMN2KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL31042529 | 0.71 | CHRM4 (0.50) | CHRM4DRD4MAPTDRD2DRD3 | |
| SCHEMBL20157033 | 0.71 | MTOR (0.47) | DRD4DRD2DRD3HTR7KDM4E | |
| SCHEMBL20140782 | 0.71 | CHRM4 (0.44) | CHRM4DRD4MAPTDRD2DRD3 | |
| SCHEMBL20150043 | 0.71 | MTOR (0.36) | DRD4SMN1; SMN2DRD2DRD3HTR7 | |
| SCHEMBL20139954 | 0.70 | POLB (0.45) | HTTMAPTGFERKDM4EALDH1A1 | |
| SCHEMBL13622664 | 0.70 | FFAR4 (0.56) | CHRM4DRD4DRD2DRD3FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |