Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 5/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 2/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.38 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140648 | 0.89 | PRMT5 (0.42) | KDM4EALDH1A1PRMT5WDR77DRD4 | |
| SCHEMBL20140513 | 0.87 | DRD4 (0.41) | KDM4EALDH1A1NPSR1DRD4DRD3 | |
| SCHEMBL20140096 | 0.87 | PARP1 (0.45) | KDM4EALDH1A1PRMT5WDR77DRD4 | |
| SCHEMBL20157255 | 0.80 | MTOR (0.40) | KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL20141292 | 0.78 | BDKRB1 (0.47) | KDM4EALDH1A1NPSR1DRD4DRD3 | |
| SCHEMBL20140667 | 0.76 | TRPC5 (0.42) | KDM4EALDH1A1DRD4DRD3DRD2 | |
| SCHEMBL20139958 | 0.74 | NAMPT (0.53) | KDM4EALDH1A1DRD4DRD3DRD2 | |
| SCHEMBL20156995 | 0.74 | TRPC5 (0.46) | KDM4EALDH1A1DRD4DRD3DRD2 | |
| SCHEMBL20139955 | 0.74 | KDM4E (0.52) | KDM4EALDH1A1NPSR1DRD4DRD3 | |
| SCHEMBL20139967 | 0.74 | NAMPT (0.48) | KDM4EALDH1A1DRD4DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |