Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15008622 | 1.00 | ADRB1 (0.36) | ADRB1CA12CA1CA2CA9 | |
| SCHEMBL6543170 | 0.81 | HTT (0.42) | CA12CA1CA2CA9CA14 | |
| SCHEMBL21753071 | 0.80 | MAPT (0.37) | ADRB1CA12CA1CA2CA9 | |
| SCHEMBL27561229 | 0.79 | SLC6A2 (0.44) | ADRB1GPR119HTR2CUSP2ALDH1A1 | |
| SCHEMBL23301320 | 0.78 | SLC6A2 (0.49) | HTR2CALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20140971 | 0.77 | SLC6A2 (0.53) | ADRB1HTR2CUSP2ALDH1A1TSHR | |
| SCHEMBL9396845 | 0.77 | SLC6A2 (0.53) | ADRB1HTR2CUSP2ALDH1A1TSHR | |
| SCHEMBL5394683 | 0.76 | NOTUM (0.43) | HTR2CALDH1A1TSHRSLC6A2SLC6A4 | |
| SCHEMBL5536717 | 0.76 | ALDH1A1 (0.55) | ADRB1GPR119USP2ALDH1A1TSHR | |
| SCHEMBL27613840 | 0.76 | HTR3E (0.45) | ADRB1HTR2CALDH1A1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |