Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140941 | 0.84 | GRM1 (0.46) | LMNAALDH1A1CHRM4SLC6A9 | |
| SCHEMBL29180966 | 0.75 | ESR1 (0.44) | ESR1ESR2MAPTALDH1A1TSHR | |
| SCHEMBL29180961 | 0.75 | ESR1 (0.44) | ESR1ESR2MAPTALDH1A1TSHR | |
| SCHEMBL30837317 | 0.75 | ESR1 (0.44) | ESR1ESR2MAPTALDH1A1TSHR | |
| SCHEMBL25154269 | 0.73 | DRD4 (0.53) | MAPTKCNH2ADORA2AADORA1CHRM4 | |
| SCHEMBL20157463 | 0.72 | GRM1 (0.41) | ALDH1A1CHRM4NOTUM | |
| SCHEMBL20140098 | 0.70 | ALDH1A1 (0.56) | MAPTALDH1A1RAB9ANOTUM | |
| SCHEMBL20140126 | 0.67 | MTOR (0.53) | LMNAALDH1A1KCNH2 | |
| SCHEMBL18436327 | 0.67 | CTSB (0.51) | MAPTLMNAMEN1KMT2ATSHR | |
| SCHEMBL20818283 | 0.67 | ALDH1A1 (0.48) | MAPTLMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |