Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 6/20 | 0.49 |
| ▸ | DRD3 | P35462 | 6/20 | 0.49 |
| ▸ | DRD2 | P14416 | 5/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.48 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20142241 | 0.86 | MTOR (0.61) | ALDH1A1KDM4EPLA2G1BRAB9AATG4B | |
| SCHEMBL20140126 | 0.85 | MTOR (0.53) | ALDH1A1KDM4EDRD4DRD3DRD2 | |
| Hydrochloric Acid SCHEMBL20140671 | 0.84 | MTOR (0.52) | ALDH1A1KDM4EDRD4DRD3DRD2 | |
| SCHEMBL20140202 | 0.83 | HTR7 (0.55) | ALDH1A1KDM4EPLA2G1BRAB9AATG4B | |
| SCHEMBL20141432 | 0.82 | MTOR (0.50) | ALDH1A1KDM4EDRD4DRD3DRD2 | |
| SCHEMBL20139928 | 0.81 | MTOR (0.56) | ALDH1A1KDM4EPLA2G1BRAB9AATG4B | |
| SCHEMBL20156824 | 0.81 | MTOR (0.56) | ALDH1A1KDM4EPLA2G1BRAB9AATG4B | |
| SCHEMBL20141569 | 0.79 | RAB9A (0.46) | ALDH1A1KDM4EPLA2G1BRAB9AATG4B | |
| SCHEMBL20157082 | 0.79 | MYC (0.54) | ALDH1A1KDM4EHTR7ATMMAPT | |
| SCHEMBL20141395 | 0.78 | PKM (0.45) | ALDH1A1KDM4EPLA2G1BRAB9AATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |