Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.53 |
| ▸ | ME2 | P23368 | 3/20 | 0.52 |
| ▸ | ME1 | P48163 | 3/20 | 0.52 |
| ▸ | ME3 | Q16798 | 3/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | SLC27A1 | Q6PCB7 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31589397 | 0.88 | HTR1A (0.52) | ME2ME1ME3KDM4EPKM | |
| SCHEMBL20804512 | 0.86 | ALDH1A1 (0.56) | HRH3ME2ME1ME3CHRM1 | |
| SCHEMBL22105683 | 0.86 | AOC3 (0.53) | HRH3ME2ME1ME3CHRM1 | |
| SCHEMBL31590771 | 0.83 | MGLL (0.61) | ME2ME1ME3KDM4EPKM | |
| SCHEMBL31589274 | 0.83 | MGLL (0.53) | ME2ME1ME3KDM4E | |
| SCHEMBL21551525 | 0.82 | ME2 (0.66) | ME2ME1ME3SMN1; SMN2LMNA | |
| SCHEMBL22105560 | 0.82 | KDM4E (0.52) | HRH3ME2ME1ME3CHRM1 | |
| SCHEMBL2456399 | 0.81 | ME2 (0.47) | ME2ME1ME3KDM4ESMN1; SMN2 | |
| SCHEMBL3832779 | 0.81 | ME2 (0.47) | ME2ME1ME3KDM4ESMN1; SMN2 | |
| SCHEMBL16397570 | 0.81 | PANK3 (0.57) | ME2ME1ME3CHRM1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1798735-A | 1-aryl-4- (aryloxycarbonyl) -piperazine derivatives as inhibitors of hormone sensitive lipase | NOVO NORDISK AS (DK) | 2006-07-05 | — | — | CN | claimed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| CN-1798735-A | 1-aryl-4- (aryloxycarbonyl) -piperazine derivatives as inhibitors of hormone sensitive lipase | NOVO NORDISK AS (DK) | 2006-07-05 | — | — | CN | disclosed |