Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GBA1 | P04062 | 12/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KRAS | P01116 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141517 | 0.78 | KDM4E (0.49) | ALDH1A1KDM4EATM | |
| SCHEMBL4147974 | 0.75 | POLB (0.51) | ALDH1A1GBA1NPC1RAB9AHTR3E | |
| SCHEMBL14758421 | 0.74 | ALDH1A1 (0.57) | ALDH1A1NPC1RAB9AHTR3EHTR3B | |
| SCHEMBL20339488 | 0.73 | HTR3E (0.63) | ALDH1A1NPC1RAB9AHTR3EHTR3B | |
| SCHEMBL6233177 | 0.71 | ACACB (0.53) | ALDH1A1GBA1NPC1RAB9AHTR3E | |
| SCHEMBL6186684 | 0.70 | SMN1; SMN2 (0.60) | ALDH1A1GBA1HTR3EHTR3BHTR3A | |
| SCHEMBL27631328 | 0.70 | HCRTR1 (0.49) | ALDH1A1GBA1NPC1RAB9AHTR3E | |
| SCHEMBL5462615 | 0.70 | HTR3E (0.77) | ALDH1A1NPC1RAB9AHTR3EHTR3B | |
| SCHEMBL6186542 | 0.70 | HCRTR1 (0.56) | ALDH1A1GBA1NPC1RAB9AHTR3E | |
| SCHEMBL20141569 | 0.69 | RAB9A (0.46) | ALDH1A1GBA1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |