Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.45 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.45 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141546 | 0.86 | MTOR (0.47) | MEN1KMT2AMTORRPTORMLST8 | |
| SCHEMBL20142241 | 0.85 | MTOR (0.61) | RAB9AMEN1KMT2AMTORRPTOR | |
| SCHEMBL20139928 | 0.82 | MTOR (0.56) | RAB9AMTORRPTORMLST8ALDH1A1 | |
| SCHEMBL20156824 | 0.82 | MTOR (0.56) | RAB9AMTORRPTORMLST8ALDH1A1 | |
| SCHEMBL20157082 | 0.81 | MYC (0.54) | MEN1KMT2AMAPK1ALDH1A1GAA | |
| SCHEMBL20133753 | 0.80 | MTOR (0.53) | RAB9ANPC1MAPK1MTORRPTOR | |
| SCHEMBL20141395 | 0.80 | PKM (0.45) | RAB9AMEN1KMT2AMTORRPTOR | |
| SCHEMBL20159229 | 0.79 | MTOR (0.74) | RAB9ANPC1MEN1KMT2AMAPK1 | |
| SCHEMBL20140098 | 0.79 | ALDH1A1 (0.56) | RAB9AMTORRPTORMLST8ALDH1A1 | |
| SCHEMBL20157274 | 0.78 | MTOR (0.49) | MTORRPTORMLST8ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |