Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 12/20 | 0.43 |
| ▸ | TACR3 | P29371 | 2/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140384 | 0.90 | MALT1 (0.41) | P2RX7TACR3MALT1TRPV1 | |
| SCHEMBL20157175 | 0.82 | P2RX7 (0.40) | P2RX7TACR3MALT1TRPV1 | |
| SCHEMBL20141394 | 0.76 | MTOR (0.42) | P2RX7TRPV1 | |
| SCHEMBL20140571 | 0.75 | DRD4 (0.39) | P2RX7TACR3 | |
| SCHEMBL109151 | 0.65 | P2RX7 (0.72) | P2RX7 | |
| SCHEMBL5693374 | 0.64 | TRPA1 (0.64) | MALT1TRPV1 | |
| SCHEMBL13930766 | 0.63 | TRPA1 (0.62) | TRPV1 | |
| SCHEMBL9930808 | 0.63 | P2RX7 (0.72) | P2RX7 | |
| SCHEMBL20141800 | 0.63 | MTOR (0.64) | MALT1TRPV1HSD11B1 | |
| Hydrochloric Acid SCHEMBL20139297 | 0.62 | MTOR (0.63) | MALT1TRPV1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |