Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 4/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.41 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157175 | 0.92 | P2RX7 (0.40) | MALT1P2RX7RBP4TACR3TRPV1 | |
| SCHEMBL20141643 | 0.90 | P2RX7 (0.43) | MALT1P2RX7TACR3TRPV1 | |
| SCHEMBL20141285 | 0.77 | KDM4E (0.40) | P2RX7 | |
| SCHEMBL20141393 | 0.73 | MTOR (0.42) | P2RX7TRPV1 | |
| SCHEMBL20141394 | 0.73 | MTOR (0.42) | P2RX7TRPV1 | |
| SCHEMBL20140774 | 0.71 | GSK3B (0.38) | P2RX7 | |
| SCHEMBL109151 | 0.64 | P2RX7 (0.72) | P2RX7 | |
| SCHEMBL2425939 | 0.63 | MALT1 (0.64) | MALT1TRPV1 | |
| SCHEMBL14086101 | 0.62 | MALT1 (0.51) | MALT1RBP4TRPV1 | |
| SCHEMBL7241637 | 0.62 | OPRK1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |