Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 3/20 | 0.57 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.57 |
| ▸ | HTR3B | O95264 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.57 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.57 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.50 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.48 |
| ▸ | PRKCA | P17252 | 1/20 | 0.48 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3632004 | 0.93 | HTR3E (0.64) | HTR3AHTR3EHTR3BALDH1A1HTR3D | |
| SCHEMBL14897578 | 0.84 | ALOX5 (0.46) | HTR3AHTR3EHTR3BALDH1A1HTR3D | |
| SCHEMBL14896676 | 0.84 | ALOX5 (0.46) | HTR3AHTR3EHTR3BALDH1A1HTR3D | |
| SCHEMBL6242154 | 0.83 | HTR3E (0.68) | HTR3AHTR3EHTR3BALDH1A1HTR3D | |
| SCHEMBL31195791 | 0.83 | HSD17B14 (0.47) | HTR3AHTR3EHTR3BALDH1A1HTR3D | |
| SCHEMBL12685315 | 0.81 | HTR3E (0.58) | HTR3AHTR3EHTR3BALDH1A1HTR3D | |
| SCHEMBL23114416 | 0.77 | HTR3E (0.53) | HTR3AHTR3EHTR3BALDH1A1HTR3D | |
| SCHEMBL30077085 | 0.77 | PIM1 (0.53) | HTR3AHTR3EHTR3BALDH1A1HTR3D | |
| SCHEMBL15347238 | 0.77 | PIM1 (0.53) | HTR3AHTR3EHTR3BALDH1A1HTR3D | |
| SCHEMBL15347217 | 0.76 | PRKCA (0.65) | HTR3AHTR3EHTR3BALDH1A1HTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |