Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | RBP4 | P02753 | 3/20 | 0.47 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140665 | 0.91 | PROKR1 (0.50) | DRD4RBP4SCD5MEN1KMT2A | |
| SCHEMBL17672868 | 0.87 | DRD4 (0.42) | DRD4RBP4SCD5MEN1KMT2A | |
| SCHEMBL16445706 | 0.84 | PROKR1 (0.57) | DRD4PROKR1GRM5ADRA1AHCRTR2 | |
| SCHEMBL1513265 | 0.79 | GPR119 (0.57) | — | |
| SCHEMBL29580963 | 0.79 | ADRA1A (0.49) | DRD4KMT2APROKR1ADRA1AHCRTR2 | |
| SCHEMBL3167985 | 0.79 | ADRA1A (0.49) | DRD4KMT2APROKR1ADRA1AHCRTR2 | |
| SCHEMBL10077963 | 0.79 | DRD4 (0.48) | DRD4PROKR1ADRA1AGRM2 | |
| SCHEMBL28942169 | 0.79 | RBP4 (0.50) | RBP4MEN1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL2636181 | 0.78 | RBP4 (0.49) | RBP4SCD5MEN1KMT2AHSD11B1 | |
| SCHEMBL21885656 | 0.78 | BACE1 (0.52) | RBP4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |