Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 8/20 | 0.66 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.66 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.66 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.66 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.66 |
| ▸ | CDK1 | P06493 | 1/20 | 0.66 |
| ▸ | ROS1 | P08922 | 1/20 | 0.66 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.66 |
| ▸ | CDK2 | P24941 | 1/20 | 0.66 |
| ▸ | FLT3 | P36888 | 1/20 | 0.66 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.66 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.66 |
| ▸ | CLK2 | P49760 | 1/20 | 0.66 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.66 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.66 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.66 |
| ▸ | MELK | Q14680 | 1/20 | 0.66 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.66 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.66 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL11845844 | 0.99 | ADK (0.64) | ADKDOT1LDCLK1DAPK3DYRK3 | |
| SCHEMBL11845729 | 0.88 | ADK (0.72) | ADKDOT1LDCLK1DAPK3DYRK3 | |
| SCHEMBL11840629 | 0.84 | ADK (0.72) | ADKDOT1LDCLK1DAPK3DYRK3 | |
| SCHEMBL20142559 | 0.84 | ATG7 (0.73) | ADKDOT1LDCLK1DAPK3DYRK3 | |
| SCHEMBL20141857 | 0.84 | ATG7 (0.73) | ADKDOT1LDCLK1DAPK3DYRK3 | |
| SCHEMBL11846298 | 0.83 | ADK (0.71) | ADKDOT1LDCLK1DAPK3DYRK3 | |
| SCHEMBL11841006 | 0.83 | ATG7 (0.73) | ADKDOT1LDCLK1DAPK3DYRK3 | |
| SCHEMBL20141562 | 0.82 | ADK (0.77) | ADKDOT1LDCLK1DAPK3DYRK3 | |
| SCHEMBL20141963 | 0.82 | ADK (0.77) | ADKDOT1LDCLK1DAPK3DYRK3 | |
| Water SCHEMBL11843143 | 0.80 | ADK (0.67) | ADKDOT1LDCLK1DAPK3DYRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10865208-B2 | ATG7 inhibitors and the uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2020-12-15 | — | — | US | disclosed |
| WO-2018089786-A1 | ATG7 INHIBITORS AND THE USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10865208-B2 | ATG7 inhibitors and the uses thereof | ATG7, BECN1, SQSTM1 | ADK 2059/4885DOT1L 272/4885DCLK1 2169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.