Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | FABP6 | P51161 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2016804 | 0.92 | SLC6A7 (0.47) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL2013930 | 0.92 | AKR1C3 (0.43) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL2015058 | 0.88 | GBA1 (0.45) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL2013896 | 0.87 | MAPT (0.52) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL2013318 | 0.87 | L3MBTL1 (0.53) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL2017795 | 0.87 | MEN1 (0.52) | MEN1KMT2AMAPTPKMALDH1A1 | |
| SCHEMBL2015986 | 0.85 | L3MBTL1 (0.48) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL2011899 | 0.84 | ALDH1A1 (0.44) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL2015083 | 0.83 | ALDH1A1 (0.54) | KMT2AMAPTALDH1A1LMNAL3MBTL1 | |
| SCHEMBL2013450 | 0.82 | IDE (0.45) | MEN1KMT2AMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075630-A1 | SUBSTITUTED FUSED ARYL AND HETEROARYL DERIVATIVES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2011-06-23 | — | — | WO | disclosed |