Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22179555 | 0.83 | L3MBTL1 (0.39) | L3MBTL1EPHX1POLBALDH1A1EDNRA | |
| SCHEMBL21393085 | 0.83 | POLB (0.47) | L3MBTL1EPHX1POLBKMT2AMEN1 | |
| SCHEMBL21392858 | 0.79 | TSHR (0.46) | L3MBTL1KMT2AMEN1RIPK1TSHR | |
| SCHEMBL21392796 | 0.79 | RIPK1 (0.45) | L3MBTL1EPHX1POLBRIPK1 | |
| SCHEMBL7190779 | 0.79 | MEN1 (0.45) | POLBKMT2AMEN1TSHR | |
| SCHEMBL21401879 | 0.79 | BCHE (0.38) | L3MBTL1POLBALDH1A1RIPK1 | |
| SCHEMBL20160512 | 0.76 | TSHR (0.51) | POLBALDH1A1KMT2AMEN1MAOB | |
| SCHEMBL21739363 | 0.76 | ALDH1A1 (0.46) | L3MBTL1POLBALDH1A1KMT2AAKR1C3 | |
| SCHEMBL21739351 | 0.75 | RORC (0.43) | EPHX1RIPK1 | |
| SCHEMBL21739336 | 0.75 | P2RX4 (0.45) | L3MBTL1POLBALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538087-A1 | REDOX-BASED REAGENTS FOR METHIONINE BIOCONJUGATION | The Regents of the University of California (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089951-A1 | REDOX-BASED REAGENTS FOR METHIONINE BIOCONJUGATION | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-05-17 | — | — | WO | disclosed |