Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11876582 | 0.89 | BRD4 (0.46) | L3MBTL1PKMKDM4ERXFP1TP53 | |
| SCHEMBL2010909 | 0.88 | FFAR1 (0.50) | L3MBTL1PKMKDM4ERXFP1TP53 | |
| SCHEMBL13058362 | 0.88 | L3MBTL1 (0.64) | L3MBTL1PKMKDM4EMAPTALDH1A1 | |
| SCHEMBL11875017 | 0.87 | TP53 (0.47) | L3MBTL1PKMKDM4ERXFP1TP53 | |
| SCHEMBL28326285 | 0.79 | POLB (0.58) | L3MBTL1PKMKDM4ETP53MAPT | |
| SCHEMBL15616677 | 0.77 | ALDH1A1 (0.51) | KDM4ERXFP1TP53MAPTALDH1A1 | |
| SCHEMBL15413923 | 0.77 | TP53 (0.52) | KDM4ERXFP1TP53MAPTALDH1A1 | |
| SCHEMBL784068 | 0.76 | RAB9A (0.60) | L3MBTL1KDM4EMAPTALDH1A1FFAR1 | |
| SCHEMBL31407999 | 0.76 | L3MBTL1 (0.64) | L3MBTL1PKMMAPTALDH1A1MPO | |
| SCHEMBL2008457 | 0.76 | TP53 (0.37) | L3MBTL1PKMKDM4ERXFP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011064188-A1 | INSECTICIDAL METHODS USING NITROGEN-CONTAINING HETEROAROMATIC COMPOUNDS | BASF SE (DE) | 2011-06-03 | — | — | WO | disclosed |
| US-5006532-A | Enzyme inhibitor; antiinflammatory agents | MERCK & CO. INC., INC. (US) | 1991-04-09 | — | — | US | disclosed |
| US-4904672-A | Derivatives of 3-hydroxyazabenzo[b]thiophene useful as 5-lipoxygenase inhibitors | MERCK & CO., INC. (US) | 1990-02-27 | — | — | US | disclosed |
| US-4767766-A | Derivatives of 3-hydroxyazabenzo(B)thiophene useful as 5-lipoxygenase inhibitors | MERCK & CO., INC. (US) | 1988-08-30 | — | — | US | disclosed |
| US-3963733-A | 3-(P-methoxybenzylthio)2-non-oxocarbonylic pyridines | SMITHKLINE CORPORATION (US) | 1976-06-15 | — | — | US | disclosed |