Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | ASPH | Q12797 | 1/20 | 0.48 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11875017 | 0.88 | TP53 (0.47) | FFAR1MAPTKDM4ETP53RXFP1 | |
| SCHEMBL2014297 | 0.88 | L3MBTL1 (0.58) | FFAR1MAPTKDM4ETP53RXFP1 | |
| SCHEMBL11876582 | 0.85 | BRD4 (0.46) | FFAR1MAPTKDM4ETP53RXFP1 | |
| SCHEMBL3804451 | 0.84 | ALDH1A1 (0.59) | MAPTGAAKDM4ETP53SMN1; SMN2 | |
| SCHEMBL4020440 | 0.82 | ALDH1A1 (0.49) | MAPTGAAKDM4ETP53SMN1; SMN2 | |
| SCHEMBL13058362 | 0.78 | L3MBTL1 (0.64) | FFAR1MAPTKDM4ESMN1; SMN2PKM | |
| SCHEMBL15413923 | 0.78 | TP53 (0.52) | MAPTKDM4ETP53RXFP1SMN1; SMN2 | |
| SCHEMBL6290570 | 0.78 | RAB9A (0.67) | FFAR1MAPTKDM4ETP53SMN1; SMN2 | |
| SCHEMBL29661834 | 0.77 | TP53 (0.49) | KDM4ETP53SMN1; SMN2PKML3MBTL1 | |
| SCHEMBL784516 | 0.76 | RAB9A (0.62) | FFAR1KDM4ETP53ASPHKDM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011064188-A1 | INSECTICIDAL METHODS USING NITROGEN-CONTAINING HETEROAROMATIC COMPOUNDS | BASF SE (DE) | 2011-06-03 | — | — | WO | disclosed |
| US-3963733-A | 3-(P-methoxybenzylthio)2-non-oxocarbonylic pyridines | SMITHKLINE CORPORATION (US) | 1976-06-15 | — | — | US | disclosed |