SCHEMBL201433

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13731435	0.90	S1PR1 (0.39)	ENPP3MEN1PARP1S1PR1S1PR3
	SCHEMBL2705005	0.90	S1PR1 (0.36)	ENPP3PARP1S1PR1S1PR3MAPT
	SCHEMBL203408	0.90	HSD17B1 (0.33)	S1PR1S1PR3ADRB1ADRB3GSTP1
	SCHEMBL2706695	0.89	MAPT (0.37)	S1PR1S1PR3MAPTGSTP1
	SCHEMBL2707354	0.88	AKR1B1 (0.36)	ENPP3PARP1ENPP1ADRB1ADRB3
	SCHEMBL19471098	0.86	ADRB2 (0.31)	S1PR1S1PR3ADRB1ADRB3
	SCHEMBL203522	0.82	PPARA (0.42)	PPARAIKBKB
	SCHEMBL201233	0.82	MAPT (0.57)	MEN1MAPTPOLBL3MBTL1KMT2A
	SCHEMBL2359911	0.81	MAPT (0.51)	MEN1MAPTPOLBNPC1RAB9A
	SCHEMBL203280	0.81	L3MBTL1 (0.59)	MEN1MAPTPOLBL3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.