SCHEMBL20143362

SCHEMBL20143362

C=C/C=C\C=C(/C)Oc1ccc(-c2ncc(C)nc2C)cc1

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
JAK3 P52333 1/20 0.43
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12901865 0.74 LMNA (0.46) KMT2ATDP1
SCHEMBL3212419 0.71 JAK3 (0.54) JAK3MEN1KMT2ATDP1
SCHEMBL20306055 0.70 TDP1 (0.36) KMT2ATDP1
SCHEMBL28068098 0.70 JAK3 (0.53) JAK3MEN1KMT2ATDP1
SCHEMBL29476058 0.70 JAK3 (0.53) JAK3MEN1KMT2ATDP1
SCHEMBL24554358 0.69 ELANE (0.34) KMT2ATDP1
SCHEMBL2120831 0.67 JAK3 (0.50) JAK3
SCHEMBL4752099 0.64 JAK3 (0.57) JAK3MEN1KMT2A
SCHEMBL3335530 0.64 JAK3 (0.56) JAK3MEN1KMT2ATDP1
SCHEMBL29476061 0.64 JAK3 (0.56) JAK3MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9972794-B2 Organometallic complex, and light-emitting element and display device using the organometallic complex SEMICONDUCTOR LABORATORY CO., LTD. (JP) 2018-05-15 US disclosed