Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.35 |
| ▸ | POLRMT | O00411 | 1/20 | 0.33 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23844121 | 0.85 | DOT1L (0.38) | DOT1LPOLRMT | |
| SCHEMBL23584717 | 0.80 | HRH4 (0.47) | DOT1LPOLRMTTNK2 | |
| SCHEMBL24606380 | 0.79 | NPC1 (0.38) | DOT1L | |
| SCHEMBL24058355 | 0.79 | DOT1L (0.33) | DOT1LPOLRMT | |
| SCHEMBL23818844 | 0.79 | POLRMT (0.35) | DOT1LPOLRMTTNK2 | |
| SCHEMBL23843995 | 0.77 | POLRMT (0.34) | DOT1LPOLRMT | |
| SCHEMBL23685890 | 0.77 | TNK2 (0.31) | POLRMTTNK2 | |
| SCHEMBL24606310 | 0.77 | DOT1L (0.36) | DOT1LPOLRMT | |
| SCHEMBL24340458 | 0.77 | POLRMT (0.43) | DOT1LPOLRMT | |
| SCHEMBL22355531 | 0.77 | POLRMT (0.43) | DOT1LPOLRMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198725-A1 | FOSALVUDINE AND FOZIVUDINE TIDOXIL FOR USE IN THE TREATMENT OF COVID-19, AND USE OF THE STRUCTURALLY SIMPLIFIED DERIVATIVES THEREOF | CHIRACON GMBH (DE) | 2021-10-07 | — | — | WO | disclosed |
| EP-3785717-A1 | METHODS FOR TREATING CORONAVIRIDAE INFECTIONS | Gilead Sciences, Inc. (US) | 2021-03-03 | — | — | EP | disclosed |
| EP-3212174-B1 | METHODS FOR TREATING FILOVIRIDAE VIRUS INFECTIONS | GILEAD SCIENCES INC (US) | 2018-05-16 | — | — | EP | disclosed |