Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18404646 | 0.80 | KMT2A (0.42) | ALDH1A1LMNARECQLKMT2AEPHX2 | |
| SCHEMBL27310599 | 0.79 | MEN1 (0.38) | KMT2AEPHX2 | |
| SCHEMBL24040378 | 0.78 | LMNA (0.31) | LMNAKMT2A | |
| SCHEMBL20805391 | 0.74 | ALDH1A1 (0.42) | TSHRALDH1A1LMNARECQLKMT2A | |
| SCHEMBL20812466 | 0.72 | ALDH1A1 (0.51) | TSHRALDH1A1RECQLCASP1CASP7 | |
| SCHEMBL21152766 | 0.72 | HTR2A (0.32) | — | |
| SCHEMBL7777350 | 0.70 | NAAA (0.37) | TSHRALDH1A1RECQLCASP1CASP7 | |
| SCHEMBL23945414 | 0.70 | HPGD (0.40) | TSHRALDH1A1LMNARECQLKMT2A | |
| SCHEMBL7777344 | 0.70 | TSHR (0.36) | TSHRALDH1A1RECQLKMT2ACASP1 | |
| SCHEMBL24514752 | 0.70 | MTNR1A (0.39) | TSHRALDH1A1KISS1RKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3321279-A1 | EXENATIDE MODIFIER AND USE THEREOF | Bright Gene Bio-Medical Technology Co., Ltd. (CN) | 2018-05-16 | — | — | EP | disclosed |