Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11922823 | 0.93 | ALDH1A1 (0.46) | ALDH1A1KDM4ETSHRSMN1; SMN2LMNA | |
| SCHEMBL10496398 | 0.84 | LMNA (0.37) | ALDH1A1KDM4ETSHRSMN1; SMN2LMNA | |
| SCHEMBL20751513 | 0.82 | ALDH1A1 (0.42) | ALDH1A1KDM4ETSHREPHX1SMN1; SMN2 | |
| SCHEMBL3429247 | 0.82 | ALDH1A1 (0.36) | ALDH1A1KDM4ETSHRSMN1; SMN2LMNA | |
| SCHEMBL9949236 | 0.81 | LMNA (0.42) | KDM4ETSHRSMN1; SMN2LMNACNR1 | |
| SCHEMBL10465441 | 0.79 | KDM4E (0.58) | ALDH1A1KDM4EEPHX1LMNAASAH2 | |
| SCHEMBL3429243 | 0.78 | KDM4E (0.34) | ALDH1A1KDM4E | |
| SCHEMBL12715979 | 0.78 | ALDH1A1 (0.41) | ALDH1A1KDM4ETSHREPHX1LMNA | |
| SCHEMBL4550651 | 0.78 | MEN1 (0.54) | ALDH1A1KDM4ELMNAASAH2MEN1 | |
| SCHEMBL299216 | 0.77 | CNR2 (0.49) | ALDH1A1KDM4ETSHREPHX1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448956-B1 | SOLID PHASE PEPTIDE SYNTHESIS OF PEPTIDE ALCOHOLS | CENTRE NAT RECH SCIENT (FR) | 2018-05-16 | — | — | EP | disclosed |