Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CETP | P11597 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | UBE2N | P61088 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28696485 | 0.98 | MEN1 (0.57) | MEN1KMT2AKDM4EASAH1ALDH1A1 | |
| SCHEMBL4432269 | 0.98 | MEN1 (0.57) | MEN1KMT2AKDM4EASAH1ALDH1A1 | |
| SCHEMBL30368691 | 0.98 | MEN1 (0.57) | MEN1KMT2AKDM4EASAH1ALDH1A1 | |
| SCHEMBL898809 | 0.98 | MEN1 (0.57) | MEN1KMT2AKDM4EASAH1ALDH1A1 | |
| SCHEMBL15239749 | 0.98 | MEN1 (0.57) | MEN1KMT2AKDM4EASAH1ALDH1A1 | |
| SCHEMBL30432362 | 0.98 | MEN1 (0.57) | MEN1KMT2AKDM4EASAH1ALDH1A1 | |
| SCHEMBL5718656 | 0.98 | MEN1 (0.57) | MEN1KMT2AKDM4EASAH1ALDH1A1 | |
| SCHEMBL2727470 | 0.98 | MEN1 (0.57) | MEN1KMT2AKDM4EASAH1ALDH1A1 | |
| SCHEMBL6237363 | 0.89 | KDM4E (0.67) | MEN1KMT2AKDM4EASAH1ALDH1A1 | |
| SCHEMBL8815031 | 0.89 | KDM4E (0.67) | MEN1KMT2AKDM4EASAH1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4226808-A | 1-Aryl-2-dihalogenodeuterioalkanoylamido-1,3-propanediol antibacterial agents | SCHERING CORPORATION (US) | 1980-10-07 | — | — | US | claimed |
| US-7518017-B2 | Fenicol compounds and methods synthesizing 2-trifluoroacetamido-3-substituted propiophenone compounds | IDEXX LABORATORIES (US) | 2009-04-14 | — | — | US | disclosed |
| US-7518017-B2 | Fenicol compounds and methods synthesizing 2-trifluoroacetamido-3-substituted propiophenone compounds | IDEXX LABORATORIES (US) | 2009-04-14 | — | — | US | disclosed |
| EP-1953138-A3 | Fenicol compounds and methods of synthesizing 2-trifluoracetamido-3-substituted propiophenone compounds | IDEXX LABORATORIES, INC. (US) | 2008-10-08 | — | — | EP | disclosed |
| EP-1953138-A2 | Fenicol compounds and methods of synthesizing 2-trifluoracetamido-3-substituted propiophenone compounds | IDEXX LABORATORIES, INC. (US) | 2008-08-06 | — | — | EP | disclosed |
| EP-1953138-A2 | Fenicol compounds and methods of synthesizing 2-trifluoracetamido-3-substituted propiophenone compounds | IDEXX LABORATORIES, INC. (US) | 2008-08-06 | — | — | EP | disclosed |
| US-20070197823-A1 | Fenicol compounds and methods synthesizing 2-trifluoroacetamido-3-substituted propiophenone compounds | IDEXX LABORATORIES, INC. | 2007-08-23 | — | — | US | disclosed |
| US-20070197823-A1 | Fenicol compounds and methods synthesizing 2-trifluoroacetamido-3-substituted propiophenone compounds | IDEXX LABORATORIES, INC. | 2007-08-23 | — | — | US | disclosed |
| US-4361557-A | 1-Aryl-2-acylamido-3-fluoro-1-propanol acylates, methods for their use as anti-bacterial agents and compositions useful therefor | SCHERING CORPORATION (US) | 1982-11-30 | — | — | US | disclosed |
| US-4311857-A | 1-Aryl-2-acylamido-3-fluoro-1-propanol acylates, methods for their manufacture and intermediates useful therein, methods for their use as antibacterial agents and compositions useful therefor | SCHERING CORPORATION (US) | 1982-01-19 | — | — | US | disclosed |
| US-4235892-A | AROMATIC ANTIBIOTICS | Schering Corporation, Patent Dept. (US) | 1980-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197823-A1 | Fenicol compounds and methods synthesizing 2-trifluoroacetamido-3-substituted propiophenone compounds | ADRB1, ADRB2, ADRA1A | MEN1 1186/4885KMT2A 2706/4885KDM4E 2091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.