Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 6/20 | 0.54 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.54 |
| ▸ | KAT2B | Q92831 | 10/20 | 0.51 |
| ▸ | BPTF | Q12830 | 1/20 | 0.51 |
| ▸ | CCNK | O75909 | 2/20 | 0.45 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20145157 | 0.82 | KAT2B (0.52) | IL1BNLRP3KAT2BBPTFCCNK | |
| SCHEMBL20145167 | 0.81 | CCNK (0.48) | CCNKCDK12 | |
| SCHEMBL20145261 | 0.80 | IL1B (0.55) | IL1BNLRP3CCNKCDK12CDK2 | |
| SCHEMBL20144869 | 0.80 | IL1B (0.55) | IL1BNLRP3CCNKCDK12CDK2 | |
| SCHEMBL22654958 | 0.79 | IL1B (0.61) | IL1BNLRP3KAT2BBPTF | |
| SCHEMBL22654959 | 0.79 | IL1B (0.61) | IL1BNLRP3KAT2BBPTF | |
| SCHEMBL22655979 | 0.79 | IL1B (0.61) | IL1BNLRP3KAT2BBPTF | |
| SCHEMBL25798526 | 0.78 | IL1B (0.66) | IL1BNLRP3KAT2BBPTFMALT1 | |
| SCHEMBL10370056 | 0.78 | POLB (0.66) | IL1BNLRP3KAT2BBPTFMALT1 | |
| SCHEMBL15739537 | 0.77 | HCAR3 (0.56) | CCNKCDK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970207-B1 | SUBSTITUTED PIPERIDINE COMPOUNDS AND THEIR USE AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-16 | — | — | EP | disclosed |