Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DNM2 | P50570 | 6/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16840726 | 0.77 | NOS3 (0.50) | ALDH1A1HTT | |
| SCHEMBL16608745 | 0.75 | DNM2 (0.61) | TLR8ALDH1A1LMNATP53TSHR | |
| SCHEMBL28841507 | 0.74 | TLR8 (0.51) | TLR8ALDH1A1LMNATP53TSHR | |
| SCHEMBL15585264 | 0.74 | TLR8 (0.51) | TLR8ALDH1A1LMNATP53TSHR | |
| SCHEMBL8585646 | 0.74 | TLR8 (0.81) | TLR8ALDH1A1LMNATP53TSHR | |
| SCHEMBL11981453 | 0.73 | HSP90AA1 (0.46) | ALDH1A1LMNATSHRHTTCYP1A2 | |
| SCHEMBL12963699 | 0.73 | NOS3 (0.55) | TLR8ALDH1A1LMNATP53TSHR | |
| SCHEMBL25867803 | 0.72 | TLR7 (0.43) | TLR8TLR7HTTCYP1A2 | |
| SCHEMBL9911066 | 0.71 | TLR8 (0.49) | TLR8ALDH1A1LMNATP53TSHR | |
| SCHEMBL25164663 | 0.69 | NOS3 (0.42) | TLR7HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970207-B1 | SUBSTITUTED PIPERIDINE COMPOUNDS AND THEIR USE AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-16 | — | — | EP | disclosed |