Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4158091 | 0.86 | TAAR1 (0.48) | TAAR1IDO1 | |
| SCHEMBL19304391 | 0.82 | ALDH1A1 (0.38) | CHRNB4CHRNA3 | |
| SCHEMBL16692501 | 0.81 | ABCB11 (0.35) | CHRNB4CHRNA3 | |
| SCHEMBL20145485 | 0.78 | GBA1 (0.36) | GBA1CHRNB4CHRNA3IDO1TDO2 | |
| SCHEMBL1006029 | 0.78 | GBA1 (0.36) | GBA1CHRNB4CHRNA3IDO1TDO2 | |
| SCHEMBL12263051 | 0.77 | GABRA1 (0.38) | CHRNB4CHRNA3IDO1TDO2 | |
| SCHEMBL24013091 | 0.77 | APEX1 (0.40) | TAAR1 | |
| SCHEMBL30242726 | 0.77 | APEX1 (0.40) | TAAR1 | |
| SCHEMBL17661956 | 0.77 | — | — | |
| SCHEMBL19571186 | 0.77 | GBA1 (0.35) | GBA1CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3063143-B1 | AMINOHETEROARYL BENZAMIDES AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2018-05-16 | — | — | EP | disclosed |