Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12312189 | 0.77 | CES2 (0.33) | TDP1 | |
| SCHEMBL10211386 | 0.75 | TSHR (0.36) | TDP1LMNAHSD17B10 | |
| SCHEMBL6537062 | 0.74 | ALDH1A1 (0.32) | TDP1LMNAHSD17B10 | |
| SCHEMBL21166455 | 0.74 | TDP1 (0.30) | TDP1 | |
| SCHEMBL15219030 | 0.73 | TDP1 (0.36) | TDP1NOS3NOS1NOS2LMNA | |
| SCHEMBL13765285 | 0.72 | — | — | |
| SCHEMBL20082269 | 0.69 | — | — | |
| SCHEMBL29071851 | 0.68 | LMNA (0.38) | TDP1NOS3NOS1NOS2LMNA | |
| SCHEMBL8709491 | 0.68 | HMGCR (0.55) | TDP1LMNAHSD17B10 | |
| SCHEMBL12040342 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2673000-B1 | POLYMER-CARBOHYDRATE-LIPID CONJUGATES | WU NIAN (US) | 2018-05-16 | — | — | EP | disclosed |