Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1629985 | 0.78 | KDM4E (0.41) | KDM4EMAPTNPC1ALDH1A1LMNA | |
| SCHEMBL12470196 | 0.74 | RAB9A (0.31) | KDM4EMAPTNPC1PPARGRAB9A | |
| SCHEMBL10035949 | 0.74 | — | — | |
| SCHEMBL13632375 | 0.70 | PRMT6 (0.42) | KDM4EMAPTALDH1A1L3MBTL1TDP1 | |
| SCHEMBL14832687 | 0.69 | HDAC1 (0.41) | KDM4EMAPTNPC1ALDH1A1LMNA | |
| SCHEMBL14832748 | 0.69 | NPC1 (0.38) | KDM4EMAPTNPC1ALDH1A1LMNA | |
| SCHEMBL12468251 | 0.69 | RAB9A (0.36) | KDM4EMAPTNPC1PPARGRAB9A | |
| SCHEMBL916593 | 0.66 | KDM4E (0.40) | KDM4EMAPTNPC1ALDH1A1LMNA | |
| SCHEMBL4463311 | 0.66 | HDAC1 (0.39) | KDM4EMAPTNPC1ALDH1A1LMNA | |
| SCHEMBL12646685 | 0.66 | DPP4 (0.36) | KDM4EMAPTNPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2760969-B1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MAT INC (CA) | 2018-05-16 | — | — | EP | disclosed |