Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 4/20 | 0.38 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4627777 | 0.81 | HCAR3 (0.32) | — | |
| SCHEMBL14832687 | 0.80 | HDAC1 (0.41) | KDM4EMAPTALDH1A1NPC1LMNA | |
| SCHEMBL23947762 | 0.80 | ALDH1A1 (0.42) | KDM4EMAPTALDH1A1NPC1LMNA | |
| SCHEMBL1629985 | 0.78 | KDM4E (0.41) | KDM4EMAPTALDH1A1NPC1LMNA | |
| SCHEMBL4463311 | 0.77 | HDAC1 (0.39) | KDM4EMAPTALDH1A1NPC1LMNA | |
| SCHEMBL14833015 | 0.77 | KDM4E (0.43) | KDM4EMAPTALDH1A1NPC1LMNA | |
| SCHEMBL14832748 | 0.76 | NPC1 (0.38) | KDM4EMAPTALDH1A1NPC1LMNA | |
| SCHEMBL14833011 | 0.73 | KDM4E (0.35) | KDM4EMAPTALDH1A1 | |
| SCHEMBL22734817 | 0.72 | KDM4E (0.42) | KDM4EMAPTALDH1A1NPC1LMNA | |
| SCHEMBL917524 | 0.72 | NPC1 (0.37) | KDM4EMAPTALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450503-B2 | Photochromic and electrochromic compounds and methods of synthesizing and using same | SWITCH MATERIALS INC. (CA) | 2013-05-28 | — | — | US | disclosed |
| US-8450503-B2 | Photochromic and electrochromic compounds and methods of synthesizing and using same | SWITCH MATERIALS INC. (CA) | 2013-05-28 | — | — | US | disclosed |
| US-8450503-B2 | Photochromic and electrochromic compounds and methods of synthesizing and using same | SWITCH MATERIALS INC. (CA) | 2013-05-28 | — | — | US | disclosed |
| US-20110003966-A1 | PHOTOCHROMIC AND ELETROCHROMIC COMPOUNDS AND METHODS OF SYNTHESIZING AND USING SAME | SWITCH MATERIALS INC. (CA) | 2011-01-06 | — | — | US | disclosed |
| US-20110003966-A1 | PHOTOCHROMIC AND ELETROCHROMIC COMPOUNDS AND METHODS OF SYNTHESIZING AND USING SAME | SWITCH MATERIALS INC. (CA) | 2011-01-06 | — | — | US | disclosed |
| US-20110003966-A1 | PHOTOCHROMIC AND ELETROCHROMIC COMPOUNDS AND METHODS OF SYNTHESIZING AND USING SAME | SWITCH MATERIALS INC. (CA) | 2011-01-06 | — | — | US | disclosed |
| US-7777055-B2 | Photochromic and electrochromic compounds and methods of synthesizing and using same | SWITCH MATERIALS INC. (CA) | 2010-08-17 | — | — | US | disclosed |
| US-7777055-B2 | Photochromic and electrochromic compounds and methods of synthesizing and using same | SWITCH MATERIALS INC. (CA) | 2010-08-17 | — | — | US | disclosed |
| US-7777055-B2 | Photochromic and electrochromic compounds and methods of synthesizing and using same | SWITCH MATERIALS INC. (CA) | 2010-08-17 | — | — | US | disclosed |
| US-20060240197-A1 | Photochromic and electrochromic compounds and methods of synthesizing and using same | SOLUTIA CANADA INC. (CA) | 2006-10-26 | — | — | US | disclosed |
| EP-0698605-B1 | Thiophene derivatives and polymers thereof | JAPAN RES DEV CORP (JP) | 2001-11-21 | — | — | EP | disclosed |
| US-5734065-A | Thiophene derivative and the polymer thereof and methods for production thereof | RESEARCH DEVELOPMENT CORPORATION OF JAPAN (JP) | 1998-03-31 | — | — | US | disclosed |
| EP-0698605-A1 | Thiophene derivatives and polymers thereof | RESEARCH DEVELOPMENT CORPORATION OF JAPAN (JP) | 1996-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060240197-A1 | Photochromic and electrochromic compounds and methods of synthesizing and using same | TET1, HMBS, MECP2 | KDM4E 2521/4885MAPT 62/4885ALDH1A1 1393/4885 |
| US-20110003966-A1 | PHOTOCHROMIC AND ELETROCHROMIC COMPOUNDS AND METHODS OF SYNTHESIZING AND USING SAME | TET1, MECP2, EYA2 | KDM4E 2641/4885MAPT 21/4885ALDH1A1 2252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.